A Final hurdle

first_img“But then again, we would want that. We want that tag that UP doesn’t stand a chance against Ateneo,” Perasol said. “The courage, the resilience, our feeling that we need to keep moving and keep fighting no matter what the odds are. That had been our team principle.”Ateneo, meanwhile, refuses to see their No. 1 seed as an edge.“In the finals, your record in the elimination round is not a factor anymore,” said assistant coach Sandy Arespacochaga. “We finished as No. 1 but that doesn’t mean we’re still the No. 1 team [in the] Finals.”“We’ve reset [our mentality]. Our attitude heading into the finals is that we cannot take this UP team for granted,” he added.  “They certainly deserve to be in the finals. They had an excellent last two games. That certainly helped them become tougher heading into the [series].”The Eagles, in fact, don’t even want to ride on the whole defending champion label.ADVERTISEMENT Don’t miss out on the latest news and information. MOST READ “[The label] doesn’t help us in any way, it doesn’t benefit us … We don’t worry about what other people say. We worry about playing through basketball and just trying to live up to our potential,” said head coach Tab Baldwin.Ateneo went on an undefeated run in the second round before dismissing Far Eastern U in the Final Four.With Angelo Kouame, Thirdy Ravena, and a host of effective complementary players, the Blue Eagles have looked like a seamless singularity on the floor. Lights inside SMX hall flicker as Duterte rants vs Ayala, Pangilinan anew UP takes the gold as UAAP 81 top story ‘Mia’: Rom-com with a cause a career-boosting showcase for Coleen Garcia Ginebra beats Meralco again to capture PBA Governors’ Cup title Lights inside SMX hall flicker as Duterte rants vs Ayala, Pangilinan anew Photo by Tristan Tamayo/INQUIRER.netIt has been long established: Ateneo has been virtually an immovable object in UAAP Season 81, its losses in the elimination round viewed as aberrations more than anything else. And as the curtains are lifted off the men’s basketball championship series, there is no unstoppable force rushing to meet the Blue Eagles.But there is a rising tide, and University of the Philippines relishes taking on that role.ADVERTISEMENT Japeth Aguilar embraces role, gets rewarded with Finals MVP plum View comments Sports Related Videospowered by AdSparcRead Next For the complete collegiate sports coverage including scores, schedules and stories, visit Inquirer Varsity. LATEST STORIES Gretchen Barretto’s daughter Dominique graduates magna cum laude from California college Nadine Lustre’s phone stolen in Brazil Carpio hits red carpet treatment for China Coast Guard PLAY LIST 02:14Carpio hits red carpet treatment for China Coast Guard02:56NCRPO pledges to donate P3.5 million to victims of Taal eruption00:56Heavy rain brings some relief in Australia02:37Calm moments allow Taal folks some respite03:23Negosyo sa Tagaytay City, bagsak sa pag-aalboroto ng Bulkang Taal01:13Christian Standhardinger wins PBA Best Player award No.13 lucky for Orlando Bloom After winning title, time for LA Tenorio to give back to Batangas folk UP, after all, has been taking down hurdle after hurdle this season, that Maroons coach Bo Perasol doesn’t mind taking on another one.“No basketball aficionado in his right mind would probably give us a good chance,” Perasol said of the duel against Ateneo that kicks off Saturday at 3:30 p.m. at Mall of Asia Arena.FEATURED STORIESSPORTSGinebra beats Meralco again to capture PBA Governors’ Cup titleSPORTSJapeth Aguilar wins 1st PBA Finals MVP award for GinebraSPORTSGolden State Warriors sign Lee to multiyear contract, bring back ChrissBut few gave the Maroons a chance, too, against No. 2 Adamson and its twice-to-beat edge. But UP still stands, adding at least a couple more games to what’s already a remarkable season, where it barged into the Finals for the first time in 32 years.They have dubbed the championship duel as “The Battle of Katipunan” and fittingly, it opens a day after the country celebrated the supreme Katipunero, Andres Bonifacio. In reality, though, it’s hardly a battle as it is a test to see how far UP has come since getting swept in the elimination round by Ateneo. Battles are fought on even terms but the odds weigh heavily against the Maroons in this one.last_img read more

Mayo Clinic researchers find genetic mutations that increase persons risk for pancreatic

first_imgJun 19 2018Six genes contain mutations that may be passed down in families, substantially increasing a person’s risk for pancreatic cancer. That’s according to Mayo Clinic research published in the June 19 edition of the JAMA. However, because researchers found these genetic mutations in patients with no family history of pancreatic cancer, they are recommending genetic testing for all pancreatic cancer patients as the new standard of care.Currently, health care providers offer genetic testing only to pancreatic cancer patients with a family history of the disease. That accounts for just 10 percent of all pancreatic cancer cases. Research suggests these testing guidelines miss genetic predisposition to cancer in up to 90 percent of pancreatic cancer patients with no family history. This finding is significant in part because the data suggest that family members should have DNA testing to understand their risk for cancer.”This study provides the most comprehensive data to date supporting genetic testing for all pancreatic cancer patients,” say Fergus Couch, Ph.D., a senior author on the study. “This is the first study to provide estimates on the magnitude of cancer risk associated with each gene. It indicates that family history alone cannot predict who has these mutations.””Multiple genes can each increase risk of pancreatic cancer. But if genetic testing is performed only on patients with a family history of pancreatic cancer, then a small number of patients will be helped,” says Gloria Petersen, Ph.D., a Mayo Clinic researcher and senior author.Genetic testing was conducted on 3,030 pancreatic patients who were seen at Mayo Clinic between 2000 and 2016. The test results of 21 cancer genes were compared to similar results from more than 123,000 patients without pancreatic cancer. The study found six genes clearly linked to an increased risk of pancreatic cancer: BRCA1, BRCA2, CDKN2A, TP53, MLH1 and ATM. These genetic mutations were identified in 5.5 percent of all pancreatic cancer patients, including 5.2 percent of cancer patients without a family history of pancreatic cancer.Related StoriesTrends in colonoscopy rates not aligned with increase in early onset colorectal cancerUsing machine learning algorithm to accurately diagnose breast cancerNew protein target for deadly ovarian cancerPatients who have these genetic mutations are at a substantially higher risk for pancreatic cancer, but that does not definitively mean they will develop the disease.”The conclusion of this study is that we now have better molecular insights into the underlying genetic causes of pancreatic cancer,” says Raed Samara, Ph.D., a study author from QIAGEN Sciences Inc. “The comprehensive data generated from this cohort required the specific and uniform sequencing, and deep analyses of a focused set of cancer predisposition genes. The risks of developing pancreatic cancer due to mutations in these genes can be more accurately estimated than ever before because of this seminal study.” Qiagen Sciences Inc. designed the DNA testing for this researchOften, pancreatic cancer is not diagnosed until late stages, when it has spread to other parts of the body. This year, 55,000 Americans will be diagnosed with pancreatic cancer, and 44,000 American will die of the disease this year, according to American Cancer Society estimates.Further clinical trials will be needed by other researchers to replicate the findings.​ Source:https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-discovers-gene-mutations-linked-to-pancreatic-cancer-calls-for-expanded-testing/last_img read more